Study of the ventilation at ATLAS cavern UX15: air velocity and temperature around the muon chambers

The Muon Chambers of ATLAS detector cannot work under temperature differences between two opposed faces above 3 K. In addition, a low velocity of the air around the Muon Chambers is essential to avoid vibration problems. The CV group at the ST division is involved in an airflow simulation inside UX15 cavern to check air temperature and velocity profiles around the ATLAS Muon Chambers. In this paper, the status and the content of the performed theoretical studies will be explained. Three simulation models, which helped to understand the Muon Spectrometer thermal environment and the efficiency of the ventilation system at ATLAS cavern, will be presented. Besides, it will be shown how these studies support the proposal of a deeper individual Muon Chamber study

Association between the morisky medication adherence scale and medication complexity and patient prescription knowledge in primary health care

The aim of the study was to check the association of the Morisky Medication Adherence Scale with the prescription complexity and with the patient’s level of knowledge about the prescription. A cross-sectional study was conducted by means of an interview and analysis of the prescription received by patients selected at Family Health Strategy Units. A Poisson regression model with robust variance was used to describe the association between the variables. Low adherence was significantly associated with highly complex prescriptions: Prevalence Ratio (PR) = 1.53; 95 % Confidence Interval (CI) = 1.28-1.82, in comparison with low and moderate complexity. Low adherence was also significantly associated with very low levels of knowledge: regarding the highest level (third tertile), the first and second tertiles had PR = 4.44; 95 % CI = 3.26-6.06 and PR = 3.22; 95 % CI = 2.33-4.47, respectively. The Morisky scale is useful to measure low adherence, with the advantage of being an easily understood instrument, which can be quickly administered, presenting simple interpretation and applicationColegio de Farmacéuticos de la Provincia de Buenos Aire

Association between the morisky medication adherence scale and medication complexity and patient prescription knowledge in primary health care

The aim of the study was to check the association of the Morisky Medication Adherence Scale with the prescription complexity and with the patient’s level of knowledge about the prescription. A cross-sectional study was conducted by means of an interview and analysis of the prescription received by patients selected at Family Health Strategy Units. A Poisson regression model with robust variance was used to describe the association between the variables. Low adherence was significantly associated with highly complex prescriptions: Prevalence Ratio (PR) = 1.53; 95 % Confidence Interval (CI) = 1.28-1.82, in comparison with low and moderate complexity. Low adherence was also significantly associated with very low levels of knowledge: regarding the highest level (third tertile), the first and second tertiles had PR = 4.44; 95 % CI = 3.26-6.06 and PR = 3.22; 95 % CI = 2.33-4.47, respectively. The Morisky scale is useful to measure low adherence, with the advantage of being an easily understood instrument, which can be quickly administered, presenting simple interpretation and applicationColegio de Farmacéuticos de la Provincia de Buenos Aire

Barium alginate capsules for 3D immobilisation of living cells: morphology, membrane properties and permeability

Encapsulation in a barium alginate membrane is a promising strategy to obtain a three dimensional culture of living cells: membrane properties are crucial for a realistic clinical application. A one-step encapsulation technique, recently developed for controlled release of boar semen, was employed to prepare barium alginate and protamine-alginate membranes: permeability to two model molecules (haemoglobin and glucose) was evaluated. Capsules were evaluated for technological properties and scanning electron microscopy was used to examine the external morphology of the capsules and the 3D distribution of the cells within the core. The results indicate that 3D arrangement and cell shape are maintained, capsule dimensions and mechanical properties can be modulated, as well as their permeability to model molecules such as haemoglobin and glucose

The two-echelon capacitated vehicle routing problem: models and math-based heuristics

Multiechelon distribution systems are quite common in supply-chain and logistics. They are used by public administrations in their transportation and traffic planning strategies, as well as by companies, to model own distribution systems. In the literature, most of the studies address issues relating to the movement of flows throughout the system from their origins to their final destinations. Another recent trend is to focus on the management of the vehicle fleets required to provide transportation among different echelons. The aim of this paper is twofold. First, it introduces the family of two-echelon vehicle routing problems (VRPs), a term that broadly covers such settings, where the delivery from one or more depots to customers is managed by routing and consolidating freight through intermediate depots. Second, it considers in detail the basic version of two-echelon VRPs, the two-echelon capacitated VRP, which is an extension of the classical VRP in which the delivery is compulsorily delivered through intermediate depots, named satellites. A mathematical model for two-echelon capacitated VRP, some valid inequalities, and two math-heuristics based on the model are presented. Computational results of up to 50 customers and four satellites show the effectiveness of the methods developed

Usefulness of Heart Rate Variability to Identify the Risk of Falling in Huntington’s Disease

Objective: To evaluate the relationship between the HRV and the risk of falling in HD patients.Background: Huntington’s disease (HD) patients have a high prevalence of falls, on the other hand, autonomic nervous system dysfunction has been reported from early stages of the disease. However, there is lack of evidence regarding the relationship between heart rate variability (HRV) and falls in this population....Fil: Terroba Chambi, Cinthia Jennifer. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Vigo, Daniel E.. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; ArgentinaFil: Merello, Marcelo Jorge. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaInternational Congress of the Parkinson's Disease and Movement DisordersNizaFranciaInternational Parkinson and Movement Disorder Societ